منابع مشابه
The winner takes it all.
W e all make mistakes from time to time. I have made my fair share, but none of my mistakes have ever won a prize. In 2002 Lundbeck breached the UK industry code of practice in the way it advertised escitalopram (Cipralex). Escitalopram is the son of citalopram (Cipramil). The company claimed that its new drug, escitalopram was more effective than citalopram, even though the two drugs have exac...
متن کاملThe winner takes it all
We study competing first passage percolation on graphs generated by the configuration model. At time 0, vertex 1 and vertex 2 are infected with the type 1 and the type 2 infection, respectively, and an uninfected vertex then becomes type 1 (2) infected at rate λ1 (λ2) times the number of edges connecting it to a type 1 (2) infected neighbor. Our main result is that, if the degree distribution i...
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For the 500,000 new cases of colorectal cancer in the world each year, identification of patients with a worse prognosis and those who are more likely to respond to treatment is a challenge. There is an increasing body of evidence correlating genetic mutations with outcome in tumours derived from human colorectal cancer cohorts. K-ras, but not p53 or APC, mutations appear to be associated with ...
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There is increasing computational evidence that the exceptionally high vulnerability of dopaminergic neurons in Parkinson's disease may be due to their unique axonal architecture and resulting metabolic needs. A new experimental study has actually demonstrated this.
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It was five days before my first Christmas in Perth, Australia, and our family had begun to arrive the night before. As the rest of household slept, I quickly threw on a skirt and tank top and left to attend the memorial service for one of my study participants, a 57-year old Anglican minister who had died from motor neurone disease (MND). Though I feared I would be late, I could see people mil...
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ژورنال
عنوان ژورنال: Cancer Cell
سال: 2015
ISSN: 1535-6108
DOI: 10.1016/j.ccell.2015.03.016